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孤独症谱系障碍(autistic spectrum disorder,ASD)是一组严重影响儿童健康、具有显著临床和病因异质性的神经发育障碍性疾病。ASD由美国儿童精神病学家Kanner教授于1943年首次报道。该病一般3岁前发病,男女发病比例约为4∶1,其典型的临床症状包括社会交往障碍,语言交流障碍以及重复、刻板的行为。美国精神病学诊断手册第4版(DSM-Ⅳ),国际疾病分类第10版(ICD-10)和中国精
Autistic spectrum disorder (ASD) is a group of neurodevelopmental disorders with significant clinical and etiological heterogeneity that affect children’s health severely. The ASD was first reported by Professor Kanner, a U.S. pediatric psychiatrist, in 1943. The disease generally onset before the age of 3, the incidence of men and women is about 4: 1, the typical clinical symptoms include social communication disorders, language barriers and repeated, stereotyped behavior. American Psychiatric Diagnostic Manual, 4th edition (DSM-IV), International Classification of Diseases, 10th Edition (ICD-10)