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目的:观察益肺补肾方联合布地奈德干粉吸入剂治疗轻中度支气管哮喘的临床疗效。方法:收集轻中度支气管哮喘患者60例,按就诊顺序随机分为观察组与对照组各30例。观察组采用益肺补肾方中药联合布地奈德干粉吸入剂治疗,对照组单纯采用布地奈德干粉吸入剂治疗。2组疗程均为28天,观察2组患者治疗前后肺功能指标1秒用力呼气容积(FEV1)占预计值百分比、呼气流量峰值(PEF)变异率的变化情况。比较2组的临床疗效。结果:临床疗效总有效率观察组为86.7%,对照组为83.3%,2组总有效率比较,差异无显著性意义(P>0.05)。治疗后,2组FEV1占预计值百分比和PEF变异率均较治疗前升高(P<0.05),观察组2项指标均高于对照组(P<0.05)。结论:益肺补肾方联合布地奈德干粉吸入剂治疗轻中度支气管哮喘的临床疗效确切,较单纯采用西药治疗能更好地改善肺功能。
Objective: To observe the clinical efficacy of Yifei Bushen Recipe combined with budesonide dry powder inhalation in the treatment of mild to moderate bronchial asthma. Methods: Sixty patients with mild to moderate bronchial asthma were randomly divided into observation group and control group according to the order of treatment. The observation group was treated with Yifeng Bushen Recipe combined with budesonide dry powder inhalation and the control group with budesonide dry powder inhalation alone. The duration of treatment was 28 days in both groups. The changes of FEV1 percentage of predicted value and peak of expiratory flow (PEF) before and after treatment were observed in two groups before and after treatment. Compare the clinical efficacy of the two groups. Results: The total effective rate of clinical observation group was 86.7% in the control group and 83.3% in the control group. There was no significant difference in the total effective rate between the two groups (P> 0.05). After treatment, both the percentage of predicted FEV1 and the rate of PEF in two groups were significantly higher than those before treatment (P <0.05). The two indexes in the observation group were significantly higher than those in the control group (P <0.05). Conclusion: Yifei Bushen Fang combined with budesonide dry powder inhalation for the treatment of mild to moderate bronchial asthma clinical curative effect than the simple Western medicine treatment can better improve lung function.