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非酒精性脂肪性肝病(NAFLD)不仅可导致肝病相关残疾和死亡,而且与动脉粥佯硬化性心脑血管事件的高发密切相关。为此,必须重视NAFLD的防治,遗憾的是至今尚乏治疗NAFLD的特效药物,现主要根据患者的具体病情采取个体化的三阶梯疗法。 第一阶梯为基础治疗,适用于各种类型的NAFLD病例,具体包括:①改变生活方式,如节食、运动、禁酒、戒烟;②去除病因和诱因,停用肝毒药物和避免接触肝毒物质,以及纠正肠道菌群紊乱;③控制原发基础疾病或伴随疾病,旨在通过上
Non-alcoholic fatty liver disease (NAFLD) not only leads to liver-related disability and death, but also is closely related to the high incidence of atherothrombotic cardiovascular and cerebrovascular events. To this end, we must attach importance to the prevention and treatment of NAFLD, unfortunately, there is still no effective treatment of NAFLD drugs, is mainly based on the specific patient’s condition to take individual three-step therapies. The first step is based on the treatment of various types of NAFLD cases, including: ① changes in lifestyle, such as diet, exercise, alcohol, smoking cessation; ② remove the cause and incentive to disable the liver poisoning drugs and avoid contact with liver toxic substances , As well as to correct intestinal flora disorders; ③ control of primary underlying disease or concomitant diseases, designed to pass on