A novel nonenzymatic glucose sensor was successfully fabricated based on the Cu2O polyhedrons covered Cu foil.The Cu2O polyhedrons covered Cu foil was constructed via a facile,low-cost and larger scale producible method.The Cu2O polyhedrons covered Cu foil can be directly used as the working electrode of nonenzymatic glucose sensor,which present good stability and flexibility.The results indicated that the Cu2O polyhedrons modified Cu electrode(Cu2O/Cu electrode) showed high electrocatalytic activity for the oxidation of glucose in alkaline solution.There are two linear regions of glucose concentration for the glucose sensor based on Cu2O/Cu electrode,respectively in 10 mmol/L to 0.53 mmol/L(sensitivity:3029.33 mA(mmol/L) à1 cm à2) and in 0.53-7.53 mmol/L(sensitivity:728.67 mA(mmol/L) à1 cm à2). A novel nonenzymatic glucose sensor was successfully fabricated based on the Cu2O polyhedrons covered Cu foil. Cu2O polyhedrons covered Cu foil was constructed via a facile, low-cost and larger scale producible method. The Cu2O polyhedrons covered Cu foil can be directly used as the working electrode of nonenzymatic glucose sensor, which presents good stability and flexibility. These results indicate that the Cu2O polyhedrons modified Cu electrode (Cu2O / Cu electrode) showed high electrocatalytic activity for the oxidation of glucose in alkaline solution. There are two linear regions of glucose concentration for the glucose sensor based on Cu 2 O / Cu electrode, respectively in 10 mmol / L to 0.53 mmol / L (sensitivity: 3029.33 mA (mmol / L) à1 cm à2) and in 0.53-7.53 mmol / L (sensitivity: 728.67 mA (mmol / L) à1 cm à2).