1968年Berggard首先从肾小球疾病患者尿中提取出β_2;微球蛋白(β_2-microglobulin,β_2-MG)。正常人体液中β_2-MG含量较低,体液中β_2-MG含量的增高对某些疾病的诊断有一定意义。本文报道应用放射免疫分析法检测各种免疫性皮肤病患者血清β_2-MG的水平。1 材料与方法 各组皮肤病患者已为临床确诊,部分经病理活检和实验室证实。(1)SLE组16例,男4例、女12例,年 In 1968 Berggard first extracted β_2-microglobulin (β_2-MG) from the urine of patients with glomerular diseases. Normal human body fluid low β 2-MG content, body fluid β 2-MG content increased for the diagnosis of certain diseases have some significance. This article reports the application of radioimmunoassay in the detection of a variety of immune skin disease in patients with serum β 2-MG levels. 1 Materials and Methods Skin disease patients in each group has been clinically diagnosed, in part by biopsy and laboratory confirmed. (1) SLE group 16 cases, 4 males and 12 females