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目的：研究前交叉韧带（ＡＣＬ）断裂与关节软骨损伤的关系，初步探讨其损伤机制。方法：回顾研究了１９８４年１２月～１９９９年１２月收治的ＡＣＬ断裂的４１９例患者软骨损伤的发生率、部位及程度。结果：软骨损伤率随时间推移而增加，伤后１年内从急性期的２０．７％显著提高到亚慢性期的５７．２％（Ｐ＜０．００１），而慢性期较亚慢性期损伤率亦有所提高，但差异不显著（Ｐ＞０．０５）。非运动员与运动员均表现了相同的变化。各个部位的软骨损伤的发生率都逐渐提高，但内髁与外髁的损伤率在各个时期都高于其他部位。在急性期，外髁的损伤率为１４．１％，显著高于内髁的５．２％（Ｐ＜０．０５），但随时间增加这种趋势逐渐改变，内髁损伤率显著增加，由急性期的５．２％增至亚慢性期的２４．７％（Ｐ＜０．００１），慢性期又增至３８．１％（Ｐ＜０．０５），而外髁损伤率基本处于较稳定状态。软骨损伤程度亦随病程延长而加重。结论：ＡＣＬ断裂后可继发关节软骨损害，并随时间推移而加重。ＡＣＬ损伤后关节软骨的损害在伤后１年内就已很严重。ＡＣＬ原始损伤时更多的是直接暴力造成外侧结构损伤，而损伤后则主要因膝关节不稳而继发内侧结构损害。
OBJECTIVE: To study the relationship between ACL rupture and articular cartilage injury and to explore its mechanism. METHODS: The incidence, location and extent of cartilage injury in 419 patients with ACL rupture who were treated from December 1984 to December 1999 were retrospectively studied. RESULTS: The rate of cartilage injury increased with time, significantly increased from 20.7% in the acute phase to 57.2% in the subchronic phase (P <0.001) within 1 year after injury, while in the chronic phase was lower than that in the subchronic phase Rates also increased, but the difference was not significant (P> 0.05). Non-athletes and athletes have shown the same changes. The incidence of cartilage injury in all parts gradually increased, but the damage rate of the medial condyle and lateral condyle in all periods are higher than the other parts. In the acute phase, the injury rate of the lateral condyle was 14.1%, which was significantly higher than 5.2% of the medial condyle (P <0.05). However, with the increase of the time, the tendency was gradually changed, the injury rate of the medial condyle was increased significantly, Increased from 5.2% in the acute phase to 24.7% in the subchronic phase (P <0.001), and increased to 38.1% in the chronic phase (P <0.05), while the injury rate of the condyles was basically at More stable state. The extent of cartilage damage also increased with the duration of the disease. Conclusion: ACL rupture may be secondary to articular cartilage damage, and aggravated over time. Articular cartilage damage after ACL injury has been severe within 1 year of injury. The primary damage of ACL is more direct damage to the lateral structure caused by violence, but mainly due to the instability of the knee after injury secondary structural damage.