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单克隆抗体药物在恶性肿瘤治疗方面最突出的优点是选择性和特异性。单克隆抗体药物治疗恶性肿瘤主要机制有两种[1]:一是利用单克隆抗体本身来阻断癌细胞生长的信号,单克隆抗体在癌细胞膜外与生长因子竞争结合受体,阻断信号传递过程,从而阻止癌细胞的生长和扩散,诱导细胞凋亡或
The most prominent advantages of monoclonal antibody drugs in the treatment of malignant tumors are selectivity and specificity. Monoclonal antibody drug treatment of malignant tumors there are two main mechanisms [1]: First, the use of monoclonal antibodies to block the growth of cancer cells signal, monoclonal antibodies in the cancer cell membrane and growth factors compete with the receptor, blocking signal Transfer process, thereby preventing the growth and spread of cancer cells, induce apoptosis or