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目的比较乳腺癌术后患者采取仰卧位与俯卧位两种不同体位接受治疗的调强计划在靶区和危及器官上的剂量差异性,寻求乳腺癌术后调强放疗较佳的治疗体位。方法随机选取12例乳腺癌保乳术后的患者并随机分为两组,分别采取仰卧位、俯卧位两种体位扫描,应用Pinnacle9.2计划系统,设计患侧乳腺切线方向小角度展开入射的4野调强计划,在计划靶区满足处方剂量的前提下,比较分析两种体位的调强计划靶区的适形度和剂量均匀性,肺的、和平均剂量,心脏的V39和V40平均剂量等剂量学指标。结果通过对12例乳腺癌保乳术后调强计划设计中,仰卧位、俯卧位两种不同体位扫描的计划比较发现,两组计划在靶区适形性及心脏受量方面差异均无统计学意义,仰卧位调强计划靶区均匀性优于俯卧位,而俯卧位使肺得到较好的保护。结论乳腺癌术后调强放疗体位可根据患者的肺功能状况选择仰卧位或俯卧位。
Objective To compare the dosage differences between the target and the organ end-organ in two postures of supine position and prone position in postoperative patients with breast cancer, and to find a better position for postoperative IMRT of breast cancer. Methods Twelve cases of breast cancer after breast conserving surgery were selected and randomly divided into two groups. They were taken in supine position and prone position respectively. Pinnacle 9.2 planning system was used to design the small angle incision 4 strong field plan to plan the target area to meet the prescribed dose under the premise of comparative analysis of the two body position of the intensity modulation plan intensity and uniformity of the dose uniformity of the lungs and the average dose of heart V39 and V40 average Dose and other dosimetry indicators. Results Comparing the plans of two different postural scanning in supine position and prone position in 12 cases of breast cancer after breast-conserving surgery, there was no statistical difference in the conformability and cardiac tolerance between the two groups Significance of the study, supine position IMRT target uniformity is superior to the prone position, and the prone position of the lung to get better protection. Conclusions Postoperative IMRT of breast cancer patients can be supine or prone position according to the patient’s pulmonary function status.