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目的 探讨老年肺癌病人的临床特点。方法 回顾性分析 113例老年肺癌病人 (6 5岁以上 )的临床特点 ,并分析不同年龄组发病时的首发症状 ,中位生存期及不同分期接受不同治疗后的生存期比较。结果 鳞癌占 5 0 .4 % ,腺癌占 36 .3% ,其他非小细胞癌占 7.1% ,小细胞癌占 6 .2 %。 4 7.8%患者在健康普查时发现。因咳嗽、咳痰就诊占 2 3% ,以咯血为首发症状占15 .9%。高龄老年肺癌组 (80～ 90岁 )中 5 3.9%的患者采用免疫治疗或未治 ,显著高于非高龄老年肺癌组 (P <0 .0 1)。仅12 .8%的患者手术 ,也明显低于非高龄老年组 (P <0 .0 1)。 6 4 %的患者生存期在 1年或 1年以内 ,平均生存 11月。 5年生存率仅 6 .9%～ 18.8%。高龄老年组 5年生存率仅 12 .8%。各组之间同期肺癌中位生存期比较均无显著差异 (P >0 .0 5 )。高龄老年肺癌组Ⅲ～Ⅳ期治疗与否 ,生存期并无显著改善 (P >0 .0 5 )。结论 老年肺癌主要为男性病人 ,且半数为鳞癌。首发症状不典型 ,早期诊断较困难。晚期老年肺癌患者不宜采取积极的治疗 ,以支持治疗为主 ,尽量减少患者的痛苦 ,提高生活质量。
Objective To investigate the clinical features of elderly patients with lung cancer. Methods A retrospective analysis of 113 elderly patients with lung cancer (more than 65 years of age) clinical features and analysis of different age groups onset of symptoms, median survival and different stages of treatment after receiving different survival comparison. Results Squamous cell carcinoma was 50.4%, adenocarcinoma 36.3%, other non-small cell carcinoma 7.1% and small cell carcinoma 6.2%. 4 7.8% of patients were found during the health census. Due to cough, sputum treatment accounted for 23% to hemoptysis as the first symptom accounted for 15.9%. In the advanced age lung cancer group (80-90 years), 5 3.9% of the patients were immunized or not treated, which was significantly higher than that of the non-aged elderly lung cancer group (P <0.01). Only 12.8% of patients underwent surgery, which was significantly lower than that of the non-elderly (P <0.01). Sixty-four percent of patients have a 1-year or 1-year survival and an average survival of 11 months. 5-year survival rate of only 6.9% to 18.8%. The 5-year survival rate of the elderly was 12.8%. There was no significant difference in the median survival time of lung cancer between groups (P> 0.05). Elderly lung cancer group stage Ⅲ ~ Ⅳ treatment or not, no significant improvement in survival (P> 0.05). Conclusion Elderly lung cancer is mainly male patients, and half of squamous cell carcinoma. The first symptom is not typical, early diagnosis is more difficult. Advanced lung cancer patients should not take active treatment to support the treatment-based, minimize the suffering of patients and improve the quality of life.