通过文献检索收集近年来国内外有关基质细胞衍生因子(SDF1)与人类免疫缺陷病毒1型(Human im-munodeficiency virus-1,HIV-1)感染相关的研究结果,对研究结果进行整理、汇总和总结,探讨中国45个民族群体SDF1-3’A等位基因多态性分布情况。SDF1-3’A在中国45个民族群体中的分布存在种族和地域差异,无明显地域上的趋势性变化,多数民族突变频率与美国白人、高加索人及亚洲黄种人水平比较接近,但明显高于美国黑人和西班牙人。 In recent years, the research results about the correlation between SDF1 and HIV-1 infection in domestic and foreign countries were collected through literature search, and the results were collated and summarized To summarize the distribution of SDF1-3’A polymorphism in 45 ethnic groups in China. The distribution of SDF1-3’A among 45 ethnic groups in China is characterized by ethnic and regional differences and no obvious trend of geographical change. The mutation frequency of majority nationality is similar to that of Caucasian, Caucasians and Asian yellow, but significantly higher For African Americans and Hispanics.