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老君仙灵芝口服液(下简称“老君仙”)是白云山正清制药股份有限公司新研制出的纯中药制剂,具有滋补强壮、增强免疫、扶正固体、延缓衰老的功效。化学分析表明,老君仙含有灵芝多糖、十二种氨基酸、微量元素等多种生物活性物质,对神经衰弱,失眠、健忘、冠心病、高血脂、癌症、肝炎、慢性支气管炎、白细胞减少等病症有显著疗效。为探讨其疗效机理,我们对其进行了大量的药理研究,现综述如下: 1 对中枢神经系统的作用 老君仙能显著地抑制小白鼠的自发活动,增强巴比妥类药物的中枢抑制作用,能使用辐射热法测定的大白鼠痛反应潜伏期延长379％,约半数动物完全镇痛,表明具有显著的镇静和镇痛作用。
Laojunxian Lingzhi Oral Liquid (hereinafter referred to as “Laojun Xian”) is a pure Chinese medicine preparation newly developed by Baiyunshan Zhengqing Pharmaceutical Co., Ltd. It has the effects of nourishing and strengthening, enhancing immunity, strengthening solids, and delaying aging. Chemical analysis shows that Laojunxian contains many biologically active substances such as Ganoderma lucidum polysaccharides, twelve kinds of amino acids, trace elements, and so on, and it has neurasthenia, insomnia, forgetfulness, coronary heart disease, high cholesterol, cancer, hepatitis, chronic bronchitis, leucopenia, etc. The condition has a significant effect. In order to investigate its therapeutic mechanism, we conducted a large number of pharmacological studies on it, which are summarized as follows: 1 Effects on the Central Nervous System Laojunxian can significantly inhibit the spontaneous activity of mice and enhance the central inhibitory effect of barbiturates. The rat latency response measured by radiant heat was prolonged by 379%. About half of the animals had complete analgesia, indicating significant sedation and analgesia.