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MicroRNAs(miRNAs)是一类长约22 nt的非编码单链RNA分子,在转录后水平调控基因的表达。miRNA能特异性诱导靶基因mRNA降解及抑制靶基因mRNA的翻译,同时在细胞的发生、发展、增殖、分化和凋亡过程中发挥重要的调节作用[1]。目前,人类基因组中已确认的miRNAs约500个,
MicroRNAs (miRNAs) are a class of non-coding single-stranded RNA molecules about 22 nt in length that regulate gene expression at the post-transcriptional level. miRNA can specifically induce mRNA degradation of target genes and inhibit target gene mRNA translation, and play an important regulatory role in the occurrence, development, proliferation, differentiation and apoptosis of cells [1]. Currently, about 500 miRNAs have been identified in the human genome,