以《中华医学杂志》为例探讨“十二五”时期综合性医学期刊的发展策略。在加强精品力作生产方面要注意挖掘跨专业选题、丰富栏目、加强编委作用；在完善公共服务体系建设方面要加强学术期刊与大众媒体的交流，建立并完善数字化网络平台，增强服务意识；此外，要加强市场体系建设，从而实现期刊自身健康发展与服务社会的有机结合。该研究可为综合性医学期刊更好地贯彻落实《新闻出版业“十二五”时期发展规划》提供参考。“,”Strategies of general medical journals are discussed with National Medicine Journal of China as example. First and foremost, select multidisciplinary issues, arrange various columns and reinforce the functions of editoral board to strengthen the publication of high-quality works. Next, increase the communication with mass media, establish digital publishing platform and strengthen service awareness to improve the development of public service system. Last but not least, promote the market system. Thus journal development and society service can be integrated and the proper solution to implement ＂ 12th Five-Year Plan of press and publication＂ are offered.