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脑动脉硬化性痴呆发生谵妄状态时治疗方法不多,疗效不满意。我们用谷氨酸钠治疗两例疗效显著,现报道如下:例一男,54岁,干部。于1981及1984年2次发生左侧脑梗塞,右侧肢体偏瘫,语言不清,C T 检查左顶叶软化灶,脑萎缩。诊断为脑梗塞,脑动脉硬化性痴呆。20天前又发生右侧脑梗塞,左侧肢体偏瘫而入院治疗。患者乱咬家属及医护人员,吃自己身上的毛衣,模仿别人说话等呈严重谵妄状态。经用镇静剂无效。以后改用谷氨酸钠40毫升(含11.5克)加10%葡萄糖500毫升每日一次静滴。用后第三天不再乱咬人。用药至第七天谵妄状态终止,白天安静,夜间入眠。至第十天停用谷氨酸钠,但停药后三天又出现谵妄状态,症状同前。再用谷氨酸钠治疗,剂量用法同前,用药至第六天谵妄状态又全
Cerebral arteriosclerotic dementia in delirium state treatment is not much, the effect is not satisfied. We use glutamate treatment of two cases of significant effect, are reported as follows: A male, 54 years old, cadres. In 1981 and 1984, 2 cases of left cerebral infarction, right limb hemiplegia, language is unclear, C T examination of the left parietal lobe softening, brain atrophy. Diagnosis of cerebral infarction, cerebral arteriosclerosis dementia. 20 days ago, right cerebral infarction occurred again, left limb paralysis and hospitalization. Patients bite their families and health care workers, eat their own sweaters, imitating other people talk was a serious state of delirium. After using sedatives. After the switch to sodium glutamate 40 ml (11.5 g) plus 10% glucose 500 ml once daily intravenous infusion. The third day after use no longer bite people. Medication to the seventh day delirium state termination, quiet during the day, sleep at night. To the tenth day deactivation of sodium glutamate, but three days after the withdrawal of delirium state, the same symptoms. Treated with sodium glutamate, the same dose with the former, to the sixth day of treatment and delirium state