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氯丙嗪别名冬眠灵,是一良好的抗精神分裂症药。近年来,临床用于治疗心力衰竭,获得了良好效果。一、氯丙嗪制心力衰竭的机理 1.减轻心脏的后负荷。近年研究证明,氯丙嗪有阻断中枢及周围血管α受体的作用,并对动脉血管平滑肌有直接作用,能扩张强烈收缩的小动脉,因而具有强有力的血管扩张效应。动脉血管扩张,心脏的后负荷减轻,有利于心脏功能恢复。
Chlorpromazine alias winter sleep spirit, is a good anti-schizophrenia medicine. In recent years, clinical treatment of heart failure, and achieved good results. First, chlorpromazine heart failure mechanism 1. Reduce the heart’s afterload. In recent years, studies have shown that chlorpromazine blocks the central and peripheral vascular receptor α role and has a direct effect on arterial smooth muscle, can expand the contraction of aortic arteries, which has a strong vasodilator effect. Arterial dilatation, the heart after the load relief, is conducive to cardiac function recovery.