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186例肺心病中,134例有蛋白尿,50例氮质血症,6例肾衰,造成氮质血症肾衰的主要因素为心肺功能衰竭,其次是氨基甙类抗生素引起的肾损害。6例肾衰中5例与用药有关,3例直接死于急性肾衰,因此除积极纠正缺氧、避免脱水及电解质紊乱外,应用氨基甙类抗生素也必须慎重、避免并用或继用先锋霉素,按肌酐值调整剂量或间期,用药中加强对肾功能的监测,以免造成肾功衰竭。
In 186 cases of pulmonary heart disease, 134 cases had proteinuria, 50 cases of azotemia and 6 cases of renal failure. The main factors causing renal failure of azotemia were cardiorespiratory failure, followed by renal damage caused by aminoglycoside antibiotics. 6 cases of renal failure in 5 cases and drug-related, 3 cases died of acute renal failure, so in addition to actively correct hypoxia, to avoid dehydration and electrolyte disorders, the application of aminoglycosides antibiotics must also be careful to avoid or with the successor pioneer mold By adjusting the dose or interval creatinine, medication to strengthen the monitoring of renal function, so as to avoid renal failure.