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目的:研究肛管结肠直肠黑素瘤的特点及诊疗。方法:回顾性分析2001年1月至2010年1月我院诊治的14例肛管结肠直肠黑素瘤病人的临床病理资料。结果:男9例,女5例,平均年龄(65.0±4.6)(27~86)岁。肿瘤位于肛管10例(71.4%)、直肠3例(21.4%)、结肠1例(7.2%)。误诊率71.4%。明确诊断后行局部扩大切除术3例,经腹会阴联合切除术5例,左半结肠切除术1例。术后均随访,随访时间2.5～11.5年,仅2例存活至今。结论:肛管及结肠直肠黑素瘤是一种少见且预后极差、易被误诊的肿瘤。早期诊断、早期手术是目前提高生存率的方案。
Objective: To study the characteristics and treatment of colorectal melanoma in anus. Methods: The clinical and pathological data of 14 patients with colorectal melanoma from January 2001 to January 2010 in our hospital were analyzed retrospectively. Results: There were 9 males and 5 females with an average age of (65.0 ± 4.6) (27-86) years. Tumors located in the anal canal in 10 cases (71.4%), rectum in 3 cases (21.4%) and colon in 1 case (7.2%). Misdiagnosis rate of 71.4%. Clearly diagnosed in 3 cases of local excision, transabdominal perineal resection in 5 cases, left half of the colon resection in 1 case. All cases were followed up for 2.5 to 11.5 years and only 2 cases survived till now. Conclusion: Anorectal and colorectal melanoma is a rare tumor with poor prognosis and easily misdiagnosed. Early diagnosis, early surgery is the current program to improve survival.