实验动物要求具有明确的遗传背景 ,实验动物的遗传质量直接影响生物医学研究结果的准确性、重复性与科学性 ,遗传质量监测是保证实验动物遗传质量的重要措施[1] 。现在实验动物的遗传质量监测运用生化标记等表型检测方法 ,存在灵敏度低等局限性。随着分子生物学技术的发展 ,DNA Laboratory animals require a clear genetic background, the quality of the experimental animals directly affect the biomedical research results accuracy, repeatability and scientific, genetic quality monitoring is to ensure the quality of laboratory animals, an important measure [1]. Now experimental animal genetic quality monitoring using biochemical markers such as phenotypic detection methods, there are low sensitivity limitations. With the development of molecular biology technology, DNA