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利多卡因原系局部麻醉药,此后又用于治疗室性心律失常。近年来临床发现还具有下列几种新用途。一、治疗眩晕症:利多卡因可用于治疗多种原因引起的眩晕。有报告,用利多卡因每次每公斤体重1毫克加入50%葡萄糖40～60毫升中静脉注射,每日1次,治疗突然发作,有视物旋转或自身旋转,绝大部分伴有恶心、呕吐的眩晕症患者36例(其中美尼尔氏征16例,重感冒4例,椎—基底动脉供血不足2例,另14例未统计病因)。结果:用药3次后全部病例症状消失,其中注射1次即有19例症状消失。其治疗美尼尔氏症及迷路炎性水肿所致的眩晕的机制可能与通过调节植物神经系统或改善内耳微循环障碍有关。对于椎—基底动脉供血不足所致的眩晕则可能是通过直接扩张脑动脉而达到治疗作用。
Lidocaine was originally a local anesthetic, and then used to treat ventricular arrhythmias. In recent years, clinical findings also have the following new uses. First, the treatment of vertigo: Lidocaine can be used to treat dizziness caused by a variety of reasons. There are reports, with lidocaine 1 mg per kg body weight per day added 50% glucose 40 ~ 60 ml intravenous injection, 1 day, the treatment of sudden onset, depending on the material rotation or rotation, the vast majority of nausea, 36 cases of vomiting vertigo (including 16 cases of Meridian’s sign, 4 cases of severe cold, vertebrobasilar insufficiency in 2 cases, the other 14 cases did not find the cause). Results: After 3 times of treatment, the symptoms of all the cases disappeared, of which 19 cases were disappeared after one injection. Its mechanism for treating dizziness caused by Meniere’s disease and inflammatory inflammatory edema may be related to the regulation of the autonomic nervous system or the improvement of microcirculation disorder of the inner ear. Dizziness caused by insufficient blood supply to the vertebrobasilar artery may have a therapeutic effect by directly expanding the cerebral artery.