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唇腭裂是较常见的先天畸形,有关神经系统受累情况,报道甚少,我们对此进行调查,结果报道如下。 资料与方法 临床资料:835例唇腭裂均为1956～1983年在我院作过唇腭裂整复术的患者,男520例,女315例,唇裂235例,腭裂114例,唇腭裂为486例。年龄2～10岁465例,11～20岁204例,20岁以上166例。父母近亲结婚者14例,有家族史76例,有难产史154例,有其他畸形的18例,其中耳廊畸形6例,眶距大、泌尿生殖系统畸形,手指畸形各4例。 调查方法:由临床经验丰富的神经科医师进行认真检查,对母体妊娠期患病情况、服药史、生产史、生长发育史、其他畸形等作了调查,智能发育等神经系统情况列为重点。
Cleft lip and palate is a more common congenital malformations, involving the nervous system involvement, reported very little, we investigate this, the results reported below. Materials and Methods Clinical data: 835 cases of cleft lip and palate were treated in our hospital from 1956 to 1983, cleft lip and palate patients, 520 males and 315 females, cleft lip in 235 cases, cleft palate in 114 cases, Cleft lip and palate in 486 cases . 465 patients aged 2 to 10 years, 204 patients aged 11 to 20 years, 166 cases over the age of 20. There were 14 cases of close relatives’ marriage between parents and relatives, 76 cases of family history, 154 cases of dystocia, 18 cases of other deformities, 6 cases of anomalies of the ear, 4 cases of large orbital anomalies, 4 cases of genitourinary system malformations and finger deformities. Survey Methods: The clinical experience of neurologists to carry out careful examination of maternal gestational conditions, medication history, production history, growth and development history, other deformities were investigated, such as intelligent development of the nervous system as a priority.