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目的 评价Gynatron低剂量率后装腔内治疗机的疗效。方法 总结 1980年 4月~ 1986年 6月间 ,应用Gynatron后装机配合60 Co治疗机进行根治性放疗的 136例宫颈癌 ,并与镭疗及高剂量率腔内后装治疗进行比较分析。结果 除 5例失访外 ,全部患者随访超过 15年 ,随访率 96 .3% (131/136 )。Ⅱ、Ⅲ期的 10年生存率分别为 83.9%和 43.2 %。总 10年生存率为 6 3.5 %。放射性直肠炎发生率为 12 .5 % (17/ 136 ) ,放射性膀胱炎发生率 9.6 % (13/ 136 )。结论 Gynatron低剂量率后装腔内治疗系统虽然有一定局限性 ,但仍可获得较满意的疗效 ;其治疗并发症患者可以接受 ,放射性直肠炎、放射性膀胱炎发生率高于镭疗 ,低于高剂量率腔内后装放疗。
Objective To evaluate the efficacy of Gynatron low-dose rate posterior endovascular machine. Methods From April 1980 to June 1986, 136 cases of cervical cancer undergoing radical radiotherapy with Gynatron and 60 Co treatment machine were compared with radiotherapy and high dose rate endovascular treatment. Results All the patients were followed up for more than 15 years except for 5 cases lost. The follow-up rate was 96.3% (131/136). The 10-year survival rates in stages II and III were 83.9% and 43.2%, respectively. The overall 10-year survival rate was 6 3.5%. The incidence of radiation proctitis was 12.5% (17/136), and the incidence of radiation cystitis was 9.6% (13/136). Conclusion Gynatron low-dose rate posterior endovascular treatment system has some limitations, but it can still achieve satisfactory results. Its therapeutic complication is acceptable. The incidence of radiation proctitis and radioactive cystitis is higher than that of radiotherapy, High dose rate intracavity after radiation therapy.