１９９０年１月至１９９８年３月收治十二指肠乳头肿瘤６８例。Ｂ超和ＣＴ检查诊断阳性率（基本准确）分别为６５５％、８０９％。ＥＲＣＰ检查４３例，全部确诊。５８例施行手术治疗，病理检查４３例均为腺癌，周围组织浸润和远处转移与肿瘤的大小无明显关系。主要手术方式：胰十二指肠切除４２例（其中保留幽门９例），切除率７２４％，乳头肿瘤切除及乳头括约肌成形术１例，姑息性手术１５例。术后主要并发症有应激性溃疡７例（１２１％），胃潴留４例（６９％）。十二指肠乳头肿瘤多为腺癌，内镜检查是主要诊断手段，治疗上应积极争取行胰十二指肠切除 From January 1990 to March 1998, 68 cases of duodenal papillary tumors were treated. The positive rates of B-ultrasound and CT examination (basically accurate) were 65.5% and 80.9%, respectively. ERCP examination in 43 cases, all confirmed. 58 cases underwent surgical treatment. Pathological examination was performed in 43 cases with adenocarcinoma. Peripheral tissue invasion and distant metastasis were not significantly related to tumor size. The main surgical methods: 42 cases of pancreaticoduodenectomy (including 9 cases of pylorus), resection rate of 72.4%, papillary tumor resection and sphincterotomy in 1 case, palliative surgery in 15 cases. The main postoperative complications were stress ulcers in 7 cases (12.1%) and gastric retention in 4 cases (6.9%). Duodenal papillary tumors are mostly adenocarcinomas. Endoscopic examination is the main diagnostic method. Treatment should actively seek for pancreatoduodenectomy.