本文对我院1995年1月～1996年12月33例毒痢进行分析，其中脑型20例，混合型12例，休克型1例。便培养阳性率78．7％均为福氏志贺菌，临床表现有高热、呕吐、脓血便、抽搐，电解质紊乱及多脏器功能衰竭等，治疗采用先锋必，丁胺卡那，部分加服氟哌酸或利福平及抗休克应用东莨菪碱同时配用多巴胺取得较好疗效，本组治愈率为81．8％，病死率3．3％。早期便培养以明确病原并选用敏感抗生素是至关重要的。 In our hospital from January 1995 to December 1996 33 cases of dysentery were analyzed, including 20 cases of brain type, mixed type in 12 cases, shock type in 1 case. Then the positive rate of 78.7% culture are Shigella flexneri, clinical manifestations of fever, vomiting, pus and blood stool, convulsions, electrolyte disorders and multiple organ failure, the treatment of Pioneer must, Services norfloxacin or rifampicin and anti-shock scopolamine with dopamine at the same time with good efficacy, the cure rate was 81.8%, the case fatality rate of 3.3%. Early culture will be to identify a clear pathogen and the selection of sensitive antibiotics is essential.