【摘 要】
：
An efficient synthesis of substituted 1,3-dihydroisobenzofurans is developed.In this novel route,oaroylbenzaldehydes,as key intermediates,can be obtained by lea
【机 构】
：
School of Biological Science & Medical Engineering,Southeast University,School of Chemistry & Chemic
【出 处】
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Chinese Chemical Letters
论文部分内容阅读
An efficient synthesis of substituted 1,3-dihydroisobenzofurans is developed.In this novel route,oaroylbenzaldehydes,as key intermediates,can be obtained by lead tetraacetate oxidation of Naroylhydrazones of salicylaldehydes.The mild and general strategy enables the synthesis of various substituted 1,3-dihydroisobenzofurans in high yields.Moreover,this method can be applied to efficiently synthesize escitalopram.
An efficient synthesis of substituted 1,3-dihydroisobenzofurans is developed. In this novel route, oaroylbenzaldehydes, as key intermediates, can be obtained by lead tetraacetate oxidation of Naroylhydrazones of salicylaldehydes. The mild and general strategy enables the synthesis of various substituted 1,3 -dihydroisobenzofurans in high yields.Moreover, this method can be applied to efficiently synthesize escitalopram.
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