介入治疗临床实践中,冠状动脉置入支架后的内膜增生已成为支架内再狭窄的病理生理机制。因此,抑制平滑肌细胞增殖能预防再狭窄。近年采用的药物涂层支架使支架内再狭窄发生率明显下降。本研究采用随机对照试验评价经皮置入金属裸支架后短期口服雷帕霉素能否减少再狭窄发生率。2 Interventional therapy in clinical practice, coronary artery stent implantation of intimal hyperplasia has become a stent in the pathophysiology of restenosis. Therefore, inhibition of smooth muscle cell proliferation can prevent restenosis. In recent years, the use of drug-coated stent so that the incidence of stent restenosis decreased significantly. This study randomized controlled trials to evaluate the short-term oral administration of rapamycin can reduce the incidence of restenosis after percutaneous implantation of bare metal stent. 2