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目的探讨红霉素联合阿奇霉素序贯疗法治疗小儿支原体肺炎的效果。方法选取支原体肺炎患儿70例,将其随机分为两组,每组35例。对照组给予单一的阿奇霉素序贯疗法治疗,观察组给予红霉素联合阿奇霉素序贯疗法治疗,对比分析两组临床症状消失时间、临床疗效及不良反应。结果对照组治疗总有效率为77.1%,明显低于观察组的94.3%,差异有统计学意义(P<0.05);对照组咳嗽消失时间、胸片阴影消失时间、退热时间、肺部湿啰音消失时间均明显长于观察组,差异有统计学意义(P<0.05);对照组不良反应发生率为31.4%,明显高于观察组的11.4%,差异有统计学意义(P<0.05)。结论红霉素联合阿奇霉素序贯疗法治疗小儿支原体肺炎效果显著,可明显改善患儿的症状,促进康复,且不良反应少。
Objective To investigate the effect of sequential therapy with erythromycin and azithromycin in treating children with mycoplasma pneumonia. Methods Seventy children with mycoplasma pneumonia were selected and randomly divided into two groups (n = 35 in each group). The control group was given a single sequential treatment of azithromycin. The observation group was treated with sequential therapy of erythromycin and azithromycin, and the disappearance of clinical symptoms, clinical efficacy and adverse reactions were compared between the two groups. Results The total effective rate of the control group was 77.1%, which was significantly lower than that of the observation group (94.3%), the difference was statistically significant (P <0.05); the control group cough disappear time, chest shadow disappearance time, (P <0.05). The incidence of adverse reactions in the control group was 31.4%, which was significantly higher than that in the observation group (11.4%), the difference was statistically significant (P <0.05) . Conclusion Erythromycin sequential treatment with azithromycin in children with mycoplasma pneumonia is significantly effective, can significantly improve children’s symptoms, promote rehabilitation, and fewer adverse reactions.