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The effects of IL-2,IL-3,and IL-4 activities on occurrence of allergic asthma induced byspores of mushroom have been studied by measuring the IL-2,IL-3,and IL-4 activities inculture supernatants of spleen lymphocytes from guinea pigs being stimulated with Con A.The IL-4 activity(14.9±0.18 u)in the culture supernatant was higher than control group(6.7±1.5u).The IL-2 and IL-3 activities were all similar to that of the control group.The IL-4synthesis was similarly raised as the IL-4 activity.These results indicated that there is arelationship between the occurrence of allergic asthma and the increase of IL-4.
The effects of IL-2,IL-3,and IL-4 activities on occurrence of allergic asthma induced byspores of mushroom has been studied by measuring the IL-2,IL-3,and IL-4 activities inculture supernatants of spleen lymphocytes Guinea pigs being stimulated with Con A.The IL-4 activity(14.9±0.18 u)in the culture supernatant was higher than control group(6.7±1.5u).The IL-2 and IL-3 activities were all similar to that of The control group.The IL-4 synthesis was similarly raised as the IL-4 activity.These results indicated that there is relationship between the occurrence of allergic asthma and the increase of IL-4.