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晚近发现,IgA 肾病患者静脉缓慢滴注多巴胺(1.5~2.0μg/kg/min)可使肾小球滤过率(GFR)显著增高。鉴于静脉缓慢输注多巴胺对正常人及各种肾脏病患者的肾功能影响尚未明确,作者对此进行研究。165名研究对象分为5组:28名正常人基础肾小球滤过率(BGFR)≥90ml/min/1.73M~2;40例肾脏病患者(包括19例 IgA 肾病)其 BGFR≥90ml/min/1.73M~2;14例单侧肾切除后独肾健康者;58例 BGFR
It has been recently found that slow intravenous infusion of dopamine (1.5-2.0 μg / kg / min) in patients with IgA nephropathy causes a significant increase in glomerular filtration rate (GFR). In view of the slow venous infusion of dopamine on normal subjects and various renal disease renal function is not yet clear, the authors studied. 165 subjects were divided into five groups: 28 normal subjects with basal glomerular filtration rate (BGFR) ≥90ml / min / 1.73M ~ 2; 40 patients with renal disease (including 19 IgA nephropathy) min / 1.73M ~ 2; 14 cases of unilateral kidney after renal kidneys were healthy; 58 cases of BGFR