论文部分内容阅读
最近,作者报告了在新确诊尚未经治疗的胰岛素依赖型糖尿病病人中,发现了胰岛素自身抗体。这些自发性胰岛素自身抗体和发生胰岛素依赖型糖尿病(IDDM)的关系目前还不清楚。为了进一步评价胰岛素自身抗体(INSAAb)在IDDM发病中的重要性。作者对几个INSAAb高发组做了检查。分析了INSAAb与胰岛细胞抗体(ICAb)β-细胞功能障碍以及IDDM发生的关系。 检查135名对IDDM具有高发危险的受试者,其中38人ICAb阳性,97人ICAb阴性。INSAAb阳性占ICAb阳性人数的31.6％(12/38),而ICAb
Recently, the authors reported that insulin autoantibodies were found in newly diagnosed untreated insulin-dependent diabetes mellitus. The relationship between these auto-insulin autoantibodies and insulin-dependent diabetes mellitus (IDDM) is unclear. In order to further evaluate the importance of insulin autoantibodies (INSAAb) in the pathogenesis of IDDM. The authors examined several high-risk groups of INSAAb. The relationship between INSAAb and islet cell antibody (ICAb) β-cell dysfunction and the occurrence of IDDM was analyzed. Of 135 subjects with a high risk of IDDM, 38 were ICAb positive and 97 were ICAb negative. INSAAb positivity accounted for 31.6% (12/38) of ICAb-positive individuals, while ICAb