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目的了解妇女宫颈感染HPV现状,为早期防治宫颈癌提供科学依据。方法采用美国ABI7500PCR扩增仪检测妇女人类乳头瘤病毒;TCT检查采用TBS分级系统进行细胞学诊断,并进行统计分析。结果检测HPV-DNA标本3 182份,阳性308份,阳性率9.68%,其中253份标本进行TCT细胞学检测,异常者71份,占28.06%,其中不典型鳞状细胞32份,占45.07%,鳞状上皮轻度病变28份,占39.44%,鳞状上皮高度病变11份,占15.49%。结论高危型HPV-DNA定量检测可为妇女宫颈癌的早期诊断及治疗提供科学依据。
Objective To understand the status of HPV infection in women with cervical cancer and provide a scientific basis for the prevention and treatment of cervical cancer in the early stage. Methods The human papillomavirus (HPV) was detected by the American ABI 7500 PCR Amplifier. The cytology was diagnosed by TBS grading system and analyzed by TCT. Results A total of 3 182 HPV-DNA samples were detected, and 308 were positive, the positive rate was 9.68%. Totally 253 TCTs were detected by TCT cytology. Among them, 71 were abnormal, accounting for 28.06%, of which 32 were atypical squamous cells accounting for 45.07% , 28 cases of mild squamous lesions, accounting for 39.44%, 11 cases of squamous epithelial lesions, accounting for 15.49%. Conclusion The high-risk HPV-DNA test can provide a scientific basis for the early diagnosis and treatment of cervical cancer in women.