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克山病的发生与摄入硒不足有密切的关系[1,2],但它的某些流行病学特点尚不能用硒贫乏园满解释。临床医师们注意到病人在早期往往有低烧和消化道症状;从病人血液和内脏中已分离出若干病毒毒株;而且在电镜下看到克山病人心肌中有疑似病毒的异常颗粒。这使我们想到克山病有可能是一种与地方性缺硒和病毒感染的相互作用有关的疾病。 为了观察克山病病区低硒饲料和病毒感染相结合对动物心脏的影响,进行了本实验。
The occurrence of Keshan disease is closely related to the imbalance of selenium intake [1,2], but some of its epidemiological features can not yet be explained by the fact that selenium deficiency is insufficient. Clinicians have noticed that patients often have low-grade fever and gastrointestinal symptoms in the early stages. Several virus strains have been isolated from the blood and viscera of the patients and abnormal particles of the suspected virus in the myocardium of Keshan patients have been observed under electron microscopy. This reminds us of the possibility that Keshan disease is a disease associated with the interaction of local selenium deficiency and viral infection. In order to observe the influence of low selenium feed and virus infection in Keshan disease area on animal heart, this experiment was carried out.