世界上第一例“无过氧化氢酶血症”是日本耳鼻喉科医生高原滋夫发现的,所以此症也称为“高原氏病”(注意,它不是一般所说的高山病的高原病!)。高原滋夫毕业于日本冈山大学医学部,由于成绩优异,毕业后留在该校附属医院耳鼻喉科工作。当时的治疗药物还不发达,口腔内局部消毒主要是用稀过氧化氢(3％过氧化氢);对于口腔粘膜的溃疡,则主要使用硝酸银水溶液(5～20％)。高原滋夫每 The world’s first case of “no catalase” was discovered by Japanese otolaryngologist Kozo Zifu, so this disease is also known as “highland’s disease.” (Note that it is not a so-called high altitude sickness disease !). He graduated from the Okayama University School of Medicine in Japan and graduated from the otorhinolaryngology department at the Affiliated Hospital of Japan after graduating with honors. At that time, the therapeutic drugs were still underdeveloped. The local oral disinfection mainly used diluted hydrogen peroxide (3% hydrogen peroxide). For oral mucosal ulcer, the main use of silver nitrate solution (5 to 20%). Plateau Zifu each