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头孢曲松钠为第三代半合成头孢菌素类抗生素,应用广泛。国产头孢曲松钠在质量和下游适用性等方面存在一定的差距。作为头孢曲松钠生产关键的精制操作不仅关系到产品的收益,更是控制产品质量的关键步骤,因此研究析出剂、洗涤溶媒—丙酮的应用势在必行。1头孢曲松钠简介1.1通用药名CEFTRIAXONE SODIUM1.2别名头孢三嗪,头孢嗪克松,头孢氨噻三嗪,Rocephin,Monocid,Acantex,Rocefin,R139-904
Ceftriaxone sodium is the third generation semi-synthetic cephalosporin antibiotics, widely used. Domestic ceftriaxone sodium in the quality and downstream applicability there is a certain gap. As the key refining operation of ceftriaxone sodium production not only relates to product benefits, but also controls the key steps of product quality. Therefore, it is imperative to study the application of precipitating agent and washing solvent-acetone. 1 Introduction to ceftriaxone 1.1 Common name CEFTRIAXONE SODIUM1.2 Alias cefotaxime, cefaclitazone, cefotaxime triazine, Rocephin, Monocid, Acantex, Rocefin, R139-904