论文部分内容阅读
目的探讨后程大分割剂量三维适形放射治疗(3DCRT)脑胶质瘤术后残存灶的近期疗效及并发症的发生率。方法16例脑胶质瘤进入三维放射治疗组,其中星形细胞瘤Ⅰ～Ⅱ级6例,Ⅲ级7例,Ⅳ级3例。开始采用2Gy/次,1次/d,5次/周,40Gy/20次,后程采用3Gy/次,1次/d,5次/每周,30gy/10次,总剂量70～80Gy。结果除1例生存6个月死于局部复发,1例死于肺部感染,其余全部生存6个月以上。全部病例均无放射性脑损伤发生。结论后程大分割三维适形放射治疗脑胶质瘤残存灶患者有较好的近期疗效,无早期并发症,晚期并发症和远期疗效有待进一步观察。
Objective To investigate the short-term curative effect and the complication rate of postoperative residual lesions in the late-stage large-dose three-dimensional conformal radiation therapy (3DCRT) glioma. Methods Sixteen cases of glioma entered the three-dimensional radiotherapy group, including astrocytoma grade Ⅰ ~ Ⅱ in 6 cases, grade Ⅲ in 7 cases and grade Ⅳ in 3 cases. Start using 2Gy / time, 1 / d, 5 times / week, 40Gy / 20 times, the latter using 3Gy / time, 1 / d, 5 times / week, 30gy / 10 times, the total dose of 70 ~ 80Gy. Results One case died of local recurrence after 6 months, one died of pulmonary infection, and the rest survived for more than 6 months. No radiation brain injury occurred in all cases. Conclusions After the procedure of dividing the three-dimensional conformal radiation therapy in patients with residual glioma, there is a good short-term curative effect. No early complications, advanced complications and long-term efficacy need to be further observed.