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我们对产前检查的283例孕妇(8～40周)静脉采血1毫升,稀释到100倍,用放射免疫分析法(双抗体法)测定甲胎蛋白(AFP),其中正常孕妇281例,按妊娠周数分为33组,其最高平均值为241.57±47.66ng/ml,最低平均值为26.85±4.50ng/ml。妊娠12周AFP值已超过正常人的两倍,并随妊娠周数增加而增高,21周开始明显升高,到33周达最高峰(241.57ng/ml),以后又随妊娠周数增加而递减,至40周时为73.29ng/ml。2例孕妇AFP超过本组上限532ng/ml,引产证实为胎儿畸形。
We prenatal examination of 283 pregnant women (8 to 40 weeks) venous blood 1 ml, diluted to 100 times by radioimmunoassay (double antibody method) determination of AFP, including 281 cases of normal pregnant women, according to the Gestational weeks were divided into 33 groups, the highest average of 241.57 ± 47.66ng / ml, the lowest average of 26.85 ± 4.50ng / ml. The AFP value of the 12th week of gestation was more than double that of the normal one, and increased with the increase of the number of gestational weeks. The level of AFP increased significantly from 21 weeks to the peak of 33.5 weeks (241.57ng / ml) Decreased to 73.29 ng / ml by 40 weeks. Two cases of pregnant women AFP over the upper limit of 532ng / ml, induced abortion confirmed fetal malformations.