肾小管酸中毒(RTA)是指肾小球滤过率正常而肾小管不能使尿液酸化的功能障碍。RTA有远端型及近瑞型之分。前者系远端肾小管不能保持管腔内及管周之间高坡度的氢离子梯度密度;后者系近端肾小管使尿液酸化不足的功能异常,滤过后的碳酸氢盐有15％以上不能被再吸收而随尿排出。远端型RTA曾见于慢性活动性肝炎(CAH)、隐原性肝硬化、原发性 Renal tubular acidosis (RTA) refers to dysfunction of the glomerular filtration rate that normalizes tubules to acidify the urine. RTA has far-end and near Rui-type points. The former Department of distal tubules can not maintain a high gradient between the lumen and the tube circumference hydrogen ion gradient density; the latter Department of proximal tubules urinary acidification dysfunction, filtration of bicarbonate more than 15% Can not be resorbed and excreted with urine. Distal RTA has seen in chronic active hepatitis (CAH), cryptogenic cirrhosis, primary