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面裂的整复能恢复其解剖形态,但常遗留不同程度的缺陷。在胎儿期进行唇腭裂修复术,让其在子宫内自然成长,可消除面部疤痕形成。下述实验证明对A/J鼠行宫内唇裂修复术是可行的,且妊娠鼠胎不会因此种手术的干扰而中止发育。此外也证明了鼠胎伤口愈合无疤痕形成的概念。材料与方法:在A/J鼠族系中自然唇裂发病率为7—12%,用致畸形药物苯妥英钠后可增至近100%。故常用它作为生物模型,
Facial cleft complex restoration of its anatomical form, but often leave varying degrees of defects. Cleft lip and palate repair in the fetus, let the natural growth in the womb, can eliminate facial scar formation. The following experiment proved that A / J mouse intrauterine cleft lip repair is feasible, and the pregnancy of mouse embryos will not stop the development of such surgery. In addition, the concept of scarless formation of murine wounds has also been demonstrated. MATERIALS AND METHODS: The incidence of natural cleft lip in the A / J murine family ranged from 7% to 12% and increased to nearly 100% with phenytoin, a teratogenic drug. It is often used as a biological model,