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广泛应用抗菌素治疗慢性肾盂肾炎,并不能完全消除病原性炎症而导致痊愈。因在治疗过程中微生物耐药性增加,机体防御因素降低。为了提高抗菌治疗的效果,有的作者建议应用增强机体抵抗力的药物。常采用白血生(Pentoxyl)、多种维生素、γ-球蛋白、溶菌酶(Lysozymum)等。但这些药物作用不清楚。著者报导有关白血生、地巴佐(Dibazol)和芦荟(Aloes)提出液用于慢性肾盂肾炎的治疗,研究其对机体非特异性防御因素与治疗的影响。以血的血清杀菌活性和白细胞吞噬活性作为免疫力的指标,观察了这类药物在肾盂肾炎临床的效率。对100名健康人平均值测定作为与的正常指数。为了刺激机体非特异性防御因素,开始分别给予Pentoxyl次0.3克日服三次,0.5％地巴佐溶液2ml,
Extensive use of antibiotics in the treatment of chronic pyelonephritis, and can not completely eliminate pathogenic inflammation and lead to recovery. Due to increased microbial resistance during treatment, body defenses are reduced. In order to improve the efficacy of antibacterial therapy, some authors suggest that the use of drugs to enhance the body’s resistance. Pentoxyl, multivitamins, gamma globulin, Lysozymum and the like are often used. But the effect of these drugs is not clear. The authors report the use of leukemia, Dibazol, and Aloes in the treatment of chronic pyelonephritis and investigate their effects on nonspecific defenses and therapies in the body. Blood serum bactericidal activity and leukocyte phagocytic activity as an indicator of immunity, observed the clinical efficacy of these drugs in pyelonephritis. The average of 100 healthy people was taken as the normal index. In order to stimulate the body’s nonspecific defensive factors, began to give Pentoxyl times 0.3 grams daily three times, 0.5% to Bazo solution 2ml,