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作者评价了带状疱疹免疫球蛋白(ZIG)对新生儿水痘的预防作用.ZIG是由恢复期患者的血浆制备的.间接免疫荧光试验证明在16%IgG溶液中水痘-带状疱疹(VZ)抗体效价比普通免疫球蛋白制剂约高30倍.给95名在母体子宫内接触过VZ病毒的新生儿肌肉注射0.1ml ZIG.这些新生儿的母亲在分娩前10天或分娩后3天因感染水痘发疹.
The authors evaluated the preventive effect of shingles immunoglobulin (ZIG) on neonatal chickenpox.ZIG was prepared from the plasma of convalescent patients.Indirect immunofluorescence assays demonstrated that varicella-zoster (VZ) immunosuppression in 16% The antibody titer was about 30 times higher than that of the normal immunoglobulin preparation and infants were injected intramuscularly with 0.1 ml of ZIG to 95 neonates exposed to the VZ virus in the mother’s uterus.The mothers of these newborns were inflicted 10 days before delivery or 3 days after delivery Infected with chickenpox rash.