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目的观察翼状胬肉切除术后局部滴用自体血清滴眼液对创面修复的临床疗效。方法治疗组翼状胬肉16眼采用单纯翼状胬肉切除术联合局部滴用自体血清滴眼液治疗,对照组翼状胬肉16眼采用单纯翼状胬肉切除术治疗。结果治疗组术后3d时自觉症状明显减轻,2周时11眼充血完全减退;对照组4d时畏光、流泪开始减轻,2周时6眼充血完全减退。角膜上皮平均修复时间治疗组(3.34±1.52)d与对照组(4.45±1.49)d相比差异有统计学意义(t=2.09,P<0.05)。治疗组术后11眼视力有提高,对照组4眼视力提高,两组对比差异有统计学意义(χ2=5.24,P<0.05)。治疗组1眼复发,对照组2眼复发,两组均无感染。结论翼状胬肉切除术后局部应用自体血清滴眼液可缩短角膜上皮的修复时间,减少了复发和感染机会。自体血清滴眼液制作简单,患者耐受性好。
Objective To observe the clinical effect of topical drops of autologous serum eye drops on wounds after pterygium excision. Methods Twenty-six eyes of pterygium were treated by simple pterygium excision combined with local drip and autologous serum eye drops. Sixteen eyes of control group were treated by simple pterygium excision. Results In the treatment group, the symptoms were relieved on the 3rd day after operation. In the second week, the edema in 11 eyes was completely diminished. In the control group, photophobia and tearing started to decrease on the 4th day. The average corneal epithelial repair time (3.34 ± 1.52) d and control group (4.45 ± 1.49) d, the difference was statistically significant (t = 2.09, P <0.05). Visual acuity was improved in 11 eyes of the treatment group and visual acuity of 4 eyes in the control group. There was significant difference between the two groups (χ2 = 5.24, P <0.05). One patient in the treatment group had recurrence, and two patients in the control group had recurrence. There was no infection in both groups. Conclusion Local application of autologous serum eye drops after pterygium excision can shorten the repair time of corneal epithelium and reduce the chances of recurrence and infection. Autologous serum eyedrops made simple, patient tolerance is good.