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目的探讨小儿重症肺炎合并心衰的临床特点、治疗方法及效果。方法将58例重症肺炎合并心衰患儿随机分为观察组(多巴胺联合多巴酚丁胺)和对照组(常规治疗)各29例。比较两组临床效果。结果观察组总有效率为93.3%,高于对照组的78.3%,P<0.05;观察组临床症状及体征好转时间均短于对照组,均P<0.05。两组均未发生肝、肾功能异常等严重不良反应。随访1~2个月病例无复发,未见明显后遗症。结论小儿重症肺炎合并心衰的临床治疗要充分考虑患儿的呼吸、心功能及生理等情况。多巴胺联合多巴酚丁胺是治疗本病的安全有效药物。
Objective To investigate the clinical features, treatment and effect of severe pneumonia complicated with heart failure in children. Methods Fifty-eight children with severe pneumonia complicated with heart failure were randomly divided into observation group (dopamine plus dobutamine) and control group (n = 29). The clinical effects of two groups were compared. Results The total effective rate in the observation group was 93.3%, which was higher than that in the control group (78.3%, P <0.05). The clinical symptoms and signs of the observation group were shorter than those in the control group (P <0.05). No adverse reactions such as liver and kidney dysfunction occurred in both groups. Follow-up 1 to 2 months without recurrence, no obvious sequelae. Conclusion The clinical treatment of severe pneumonia complicated with heart failure in children should give full consideration to the respiration, cardiac function and physiology of children. Dopamine combined with dobutamine is a safe and effective drug for the treatment of this disease.