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蛋白酶抑制剂治疗可极大地降低与HIV感染相关性疾病的发病率和死亡率。蛋白酶抑制剂在体外活性高,但其使用因在体内活性快速被清除而受
Protease inhibitor treatment can greatly reduce the morbidity and mortality associated with HIV infection. Protease inhibitors are highly active in vitro but their use is limited by the rapid elimination of in vivo activity