人巨细胞病毒(human cytomegalovirus,HCMV)是和输血具有密切关系的人类疱疹病毒。通过输血传播的CMV原发感染可导致免疫功能低下患者发生严重的巨细胞病毒病。输注CMV抗体阴性血制品或去白细胞血制品可减少其发生,但并不能完全幸免于难。目前正致力于利用PCR筛查含CMV的血制品、灭活血制品中病毒及对高危患者使用疫苗等预防措施的研究。 Human cytomegalovirus (HCMV) is a human herpes virus that has a close relationship with blood transfusion. Primary infection with CMV transmitted by blood transfusions can lead to severe cytomegalovirus disease in immunocompromised patients. Infusion of CMV antibody-negative blood products or leukocyte-depleted products can reduce its occurrence, but not completely survived. At present, research is being conducted on the use of PCR to screen for CMV-containing blood products, inactivating viruses in blood products and the use of vaccines in high-risk patients.