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本文测定24名正常妊妇血浆纤维蛋白原、IgM及α_2-巨球蛋白(α_2-M)的变化及其对红细胞聚集(RCA)的影响。包括初产妇14例,经产妇10例。无高血压与宫内生长停滞。分别于妊娠第14、22、30、37周及产后8周不加压抽取静脉血、产后8周作为非妊娠值。按Brinkman法测定RCA,以红细胞聚集半时间(AHT)表示。以选定红细胞浓度时的聚集半时间为纠正聚集半时间(AHTc)。整个妊娠期间纤维蛋白原浓度持续增加,IgM在妊娠头3个月明显减低,14-37周时呈持续而明显
In this paper, the changes of plasma fibrinogen, IgM and α_2-macroglobulin (α_2-M) in 24 normal pregnant women and their effects on erythrocyte aggregation (RCA) were investigated. Including primipara 14 cases, 10 cases of maternal. No high blood pressure and intrauterine growth arrest. Venous blood was drawn out without pressure during the 14th, 22th, 30th, 37th, and 8th weeks of pregnancy, respectively, and non-pregnant for 8 weeks postpartum. RCA was measured by Brinkman’s method and expressed as half-erythrocyte aggregation time (AHT). The half-time of aggregation at the selected erythrocyte concentration is the corrected half-time of aggregation (AHTc). The concentration of fibrinogen continued to increase throughout the pregnancy, IgM significantly decreased in the first trimester of pregnancy, 14-37 weeks was sustained and obvious