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目的探讨~(131)I固定计量法及计算计量法治疗甲亢疗效评价。方法回顾同济大学附属第十人民医院核医学科2009年10月至2010年2月~(131)I治疗的甲亢患者临床资料,按固定计量法及计算计量法分别进行分组,并行疗效分析。结果 96例Graves’甲亢患者~(131)I治疗后12个月固定剂量组、计算剂量组甲减发生率分别为20.83%(10/48)及22.91%(11/48),总治愈率分别为91.67%(44/48)及93.75%(45/48)。结论 ~(131)I固定计量组和计算剂量组临床结果的发生率及两组到达临床结果的时间差异无统计学意义。~(131)I固定计量法简化治疗步骤,节约治疗费用,是比较值得提倡的治疗方法。
Objective To investigate the effect of ~ (131) I fixed measurement and calculation and measurement in treating hyperthyroidism. Methods The clinical data of patients with hyperthyroidism treated by Department of Nuclear Medicine, The Tenth People ’s Hospital Affiliated to Tongji University from October 2009 to February 2010 were retrospectively analyzed. The clinical data were divided into two groups according to the fixed measurement and the calculated measurement. Results 96 cases of Graves’ patients with hyperthyroidism ~ 131 I treatment after 12 months fixed dose group, the calculated dose hypothyroidism rates were 20.83% (10/48) and 22.91% (11/48), the total cure rates were 91.67% (44/48) and 93.75% (45/48) respectively. Conclusion There was no significant difference in the clinical outcome between the ~ 131 I fixed dose group and the calculated dose group and the time to clinical outcomes between the two groups. ~ (131) I fixed measurement method simplifies the treatment steps, saving treatment costs, is more worthy of treatment.