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目的探讨胃肠间质瘤的病理组织学和免疫组织化学特点及诊断要点。方法对32例胃肠间质瘤进行常规病理及免疫组化CD34、CD117、SMA、S-100、Desmin等染色特点分析。结果 32例胃肠间质瘤中有梭形细胞和上皮样细胞组成,CD34、CD117的阳性率较高,部分病例SMA呈阳性。结论胃肠间质瘤是胃肠道常见间叶源性肿瘤,CD34、CD117、SMA、S-100等有助于胃肠间质瘤的诊断。
Objective To investigate the histopathological and immunohistochemical features and diagnosis of gastrointestinal stromal tumors. Methods 32 cases of gastrointestinal stromal tumors were analyzed by routine histopathology and immunohistochemical staining of CD34, CD117, SMA, S-100 and Desmin. Results 32 cases of gastrointestinal stromal tumors spindle cells and epithelial cells, CD34, CD117 positive rate is high, in some cases SMA was positive. Conclusion Gastrointestinal stromal tumors are common mesenchymal tumors in the gastrointestinal tract. CD34, CD117, SMA and S-100 are helpful to the diagnosis of gastrointestinal stromal tumors.