血管并发症是糖尿病死亡的主要原因。据调查,糖尿病患者的心脏疾患、坏疽、肾功能衰竭、失明的发生率远较非糖尿病者为高,糖尿病患者动脉硬化的发生时间亦较非糖尿病者为早,且发展较快,提示糖尿病中动脉硬化的病理变化与非糖尿病者不完全相同。糖尿病血管并发症包括大血管病变(动脉粥样硬化)和糖尿病特有的微血管病变。糖尿病大血管病变的发生机制主要是内皮损伤(由于免疫因素,激素不平衡,内膜细胞代谢改变)血小板粘附、聚集、释放促有丝分裂因子在损伤部位刺激平滑肌细胞增 Vascular complications are the leading cause of death from diabetes. According to the survey, diabetic patients with heart disease, gangrene, renal failure, the incidence of blindness is much higher than non-diabetic patients, atherosclerosis in diabetic patients also occurred earlier than non-diabetic patients, and the rapid development, suggesting that diabetes Pathological changes of atherosclerosis and non-diabetic are not exactly the same. Diabetic vascular complications include macrovascular disease (atherosclerosis) and diabetes-specific microangiopathies. The pathogenesis of diabetic macroangiopathy is mainly endothelial injury (due to immune factors, hormone imbalance, changes in the metabolism of endometrial cells) platelet adhesion, aggregation, release of mitogenic factors in the injury site to stimulate smooth muscle cells increased