论文部分内容阅读
本文采用小鼠淋巴细胞微核测定技术,对不同海拔高度(平原(46m)、中度海拔(2260m)、特高海拔(模拟6000m)、不同紫外线强度(大、小剂量)照射和减压6000m加紫外线照射的NIH系小白鼠进行了微核测定。结果表明:随着低氧程度的加重和紫外线照射强度的增加,都可使小鼠微核率显著增高;而且低氧加紫外线双重因素作用对小鼠微核率的影响具有协同作用。说明强烈的紫外线和低氧可诱发机体染色体畸变,且二者似科有协同致畸作用。揭示我们不能轻视高原紫外线对机体的损伤,应加强综合防护。
In this study, the micronucleus test of mouse lymphocytes was used to study the effects of irradiation on different altitudes (46m, medium elevation (2260m), extra-high altitude (simulated 6000m), different ultraviolet intensities The micronucleus test of NIH mice irradiated with ultraviolet ray showed that the micronucleus rate of mice was significantly increased with the increase of hypoxia and the increase of ultraviolet radiation intensity and the dual factor of hypoxia and ultraviolet On mice micronucleus rate has a synergistic effect.It shows that strong UV and hypoxia can induce body chromosomal aberration, and both have similar synergistic teratogenic effects.We reveal that we can not neglect the plateau ultraviolet damage to the body, should strengthen the comprehensive Protection.