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目的：研究输精管结扎大鼠Ｔ淋巴细胞功能的变化。方法：应用生物学方法检测了输精管结扎６月和１６月大鼠胸腺细胞自身增殖反应性、ＣｏｎＡ诱导的脾细胞增殖反应性以及培养上清中ＩＬ－２活性。结果：①胸腺细胞自身增殖反应性，ＶＧ与ＳＯＧ比较无显著差异；②ＣｏｎＡ诱导的脾细胞增殖反应性和ＩＬ－２活性，ＶＧ６明显低于ＳＯＧ６（Ｐ＜０．０１，Ｐ＜０．０５）；而ＶＧ２５和ＳＯＧ２５比较无明显差异。结论：输精管结扎早期，成熟Ｔ细胞功能暂时性降低，但对Ｔ淋巴细胞分化成熟过程无影响
Objective: To study the changes of T lymphocyte function in vasectomized rats. Methods: The proliferative reactivity of thymocytes, the proliferative reactivity of splenocytes induced by Con A and the activity of IL-2 in culture supernatants were detected by biological methods in June and June of vasectomy. Results: (1) Thymocyte proliferative reactivity was not significantly different between VG and SOG; (2) ConA induced proliferation and IL-2 activity of spleen cells, VG6 was significantly lower than that of SOG6 (P <0.01, P <0.05) ; While VG25 and SOG25 no significant difference. Conclusion: In the early period of vasectomy, the function of mature T cells is temporarily decreased, but it has no effect on the differentiation and maturation of T lymphocytes