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目的：研究恒牙列初期骨性安氏Ⅱ类错牙合的颅颌结构变化，确立该类错牙合的矫治时机．方法：随机抽取临床４０例恒牙列初期的安氏Ⅱ类１分类错牙合患者，进行近１年时间的观察．对观察前、后患者的侧位定位ｘ线头影片做Ｄｏｗｎｓ法测量分析及配对ｔ检验．结果：处于恒牙列初期的女性患者，上下颌骨关系已无明显变化，但上颌切牙表现的更加前突，下颌切牙更加舌倾；男性患者的下颌骨表现为向前、向上方向旋转生长，其变化数值有统计学意义．结论：对骨性安氏Ⅱ类错牙合患者需及早施以矫治．
Objective: To study the craniofacial structure changes of skeletal class Ⅱ malocclusion in the early stage of permanent dentition and to establish the timing of orthodontic treatment. Methods: A total of 40 patients with clinically normal early stage Class II and Division 1 malocclusion were enrolled in this study. The patients were observed for nearly one year. Downs-method measurement and paired t-test were performed on the X-ray films of lateral and lateral positioning of the patients before and after the observation. Results: In the early stage of permanent dentition, the relationship between the mandible and mandibular had no significant change, but the maxillary incisors showed more protrusion and the mandibular incisors were more tongue-lipped. The mandible of male patients showed forward and upward rotation Growth, the value of the change was statistically significant. Conclusion: Patients with skeletal Class Ⅱ malocclusion should be treated as soon as possible.